Unique distribution of glycoprotein receptors on parenchymal and sinusoidal cells of rat liver.
نویسندگان
چکیده
منابع مشابه
Hemoglobin and erythrocyte catabolism in rat liver: the separate roles of parenchymal and sinusoidal cells.
متن کامل
Heterogeneous distribution of transferrin receptors on parenchymal and nonparenchymal liver cells: biochemical and morphological evidence.
To investigate which cells of the liver express the receptor for transferrin, isolated rat liver cells produced by collagenase perfusion were fractionated by repeated differential centrifugation to produce hepatocytes (95% + 1%, mean +/- SD, n = 4) and nonparenchymal cells (97% + 1%, n = 3). Saturable, high-affinity binding of 125I-transferrin was demonstrated on intact cells at 4 degrees C, wi...
متن کاملHeterogeneous Distribution of Transferrin Receptors on Parenchymal and Nonparenchymal Liver Cells
To investigate which cells of the liver express the receptor for transferrin. isolated rat liver cells produced by collagenase perfusion were fractionated by repeated differential centrifugation to produce hepatocytes (95% + 1 %. mean ± SD, n 4) and nonparenchymal cells (97% + 1 %, n = 3). Saturable. high-affinity binding of ‘2 l-transferrin was demonstrated on intact cells at 4 #{176}C. with a...
متن کاملIdentification of a novel glycoprotein (AGp110) involved in interactions of rat liver parenchymal cells with fibronectin
We have identified an integral membrane glycoprotein in rat liver that mediates adhesion of cultured hepatocytes on fibronectin substrata. The protein was isolated by affinity chromatography of detergent extracts on wheat germ lectin-Agarose followed by chromatography of the WGA binding fraction on fibronectin-Sepharose. The glycoprotein (AGp110), eluted at high salt concentrations from the fib...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1979
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(17)30031-5